Quinidine Therapy after Mitral Valvotomy

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Quinidine Therapy after Mitral Valvotomy

Nearly half a century has passed since quinidine was first used to convert atrial fibrillation to regular sinus rhythm in man (Frey, 1918). There is general agreement nowadays that the cardiorespiratory benefits resulting from the successful reversion of long-standing atrial fibrillation to sinus rhythm are worth the risk of quinidine therapy (Hay, 1924; Stroud, LaPlace, and Reisinger, 1932; Ko...

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Ouinidine therapy after mitral valvotomy.

Nearly half a century has passed since quinidine was first used to convert atrial fibrillation to regular sinus rhythm in man (Frey, 1918). There is general agreement nowadays that the cardiorespiratory benefits resulting from the successful reversion of long-standing atrial fibrillation to sinus rhythm are worth the risk of quinidine therapy (Hay, 1924; Stroud, LaPlace, and Reisinger, 1932; Ko...

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Deterioration after mitral valvotomy.

It is now more than ten years since the introduction of mitral valvotomy. The initial results (Baker, Brock, and Campbell 1950; Baker et al., 1952) and a three-year follow-up of the first 45 Guy's cases (Baker et al., 1955) have been published. We now report a larger group of 200 patients followed up for over five years, which allows a more complete assessment of the long-term benefits of mitra...

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Ineffectiveness of quinidine in preventing atrial fibrillation following mitral valvotomy.

ATRIAL FIBRILLATION is a frequent, undesirable complication of mitral valvotomy in patients with sinus rhythm. The reported high incidence of this complication (23 to 50%) 1-7 has been the basis for advocating the prophylactic use of quinidine by Black and associates7 and Kittle and Crockett.3 Black and associates have reported reducing the postoperative incidence of atrial fibrillation from 42...

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Electroconversion of atrial fibrillation after mitral valvotomy.

Of a series of IOO consecutive patients undergoing closed mitral valvotomy, 84 were in atrial fibrillation after operation. Fifty-six were treated by DC countershock; 7 returned to sinus rhythm without defibrillation, and in the remaining 2I defibrillation was not attempted. Of those patientsfibrillatingfor more than a year, none remained in sinus rhythm one year after defibrillation, and no pa...

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ژورنال

عنوان ژورنال: Thorax

سال: 1962

ISSN: 0040-6376

DOI: 10.1136/thx.17.3.274